brain — overview

Tuesday, 04 August 2026 · Regenerated 2026-08-04 06:13

Today 0 due today

Inbox — needs your attention

Triage (your 2026-08-03 note, for today): GMS 2754/2751 — revise your sections · MECFS grant — adapt budget to CellTrend pricing · RMU Initiativfonds — worth it? scout Mainz/Darmstadt AI partners [inbox]

DZHK GMS 2754/2751 review questions (Schiattarella fwd) → filed to data-harmonization-grant ## Inbox; action: revise your sections [inbox]

DZHK HFpEF Retreat — slot planning (Schiattarella fwd) → docs in 00-inbox/discuss/ (Retreat_2026.xlsx, Focus-area data-generation DE+EN, HFpEF-Sessions proposal); action: plan/return your slots [inbox]

AURORA associated partnership (DFKI/Vollgraf fwd) → call Peter Ecker today 11:00 (calendar); LoS + Kurzinfo templates in 00-inbox/discuss/Aurora/; action: Letter of Support only, no data [inbox]

MECFS/CellTrend pricing agreed €161,460 (Heidecke fwd) → filed to mecfs-merf note; action: adapt MERF budget + request formal Angebot [inbox]

Titus Kühne (DHZC) re BMFTR e2Health in-silico — "schon dran", open to co-apply, wants a Berlin meet (networking; no urgent action) [inbox]

2026-07_Informationen-Projekte-Personen.xlsx → in 00-inbox/discuss/; implied: review/sort (persistent) [inbox]

HerzCheck/We-Care-HF_CMR Data-Transfer-Agreement.docx → in 00-inbox/discuss/; implied: review/sign DTA (persistent) [inbox]

Due today

When	Item	Actions
No tasks due today

Today's calendar — Tuesday, 4 August 2026

Time	Slot	What
10:00–11:00	Admin	Schöffner
11:00–11:30	Strategy	Call Peter Ecker (DFKI) — AURORA HFpEF associated partnership (LoS ask; templates in 00-inbox/discuss/Aurora/)

Note about Today (autosaves; send when ready)

Bring up @c — discuss or sort 3

nixdorff-epc/STATE.md: Uwe reply — re-discuss Studienkonzeptskizze, support the Vorläuferstudie, host Doktoranden/Werksstudenten at FFM; wants to confer next week. [@c]

lerbs-msc-thesis/STATE.md: check Prof. Simeon Sauer's fit as HS-Mannheim supervising prof / 1st examiner before Ilka registers. [@c]

20-company/traiectories (fwd 08-02): Zeit article on cancer types/risk/prevention — Eike asks "pit into trAIectories?"; discuss the longitudinal-report angle (filed to traiectories/STATE.md). [@c]

Note about these (autosaves; send when ready)

Next 7 days — Tue 04 Aug → Mon 10 Aug 0 deadlines

Deadlines

show all (incl. items in someone else's court)

Day	Item	Actions
No deadlines this week

Open decisions across the brain

Define the decision-queue format in the overview (science gates lane). [science-harvester]

Then template the **paper-writing harvester (secondary use / thin slice)** — pick one proven dataset, run a thin-slice secondary paper through HiWi+AI to template the pattern (revision/rebuttal grind folds in). [science-harvester]

Operator hire: TR to recruit 2–3 bright HiWis (one for EN); EN runs them; no-delivery=contract-end. Write the operator playbook (so the role survives turnover). [science-harvester]

**Double-win:** the rule sets / playbooks we co-build ARE the substance of the trustworthy-AI manuscript (`10-research/trustworthy-ai-science/`) — build once, use twice. [science-harvester]

**Build the grant-harvester template from the just-shipped DFG (NA 925/4-1)** — extract the reusable pipeline + decision-gate checklist. [High]  (parked 2026-07-17, Eike) [science-harvester]

Note about this week (autosaves; send when ready)

Parked questions ?c? — for later 0

No parked questions.

Delegations 1 need you · 6 quiet (hidden) · 7 total

Status: Who: show all (incl. parked / running / returned)

Who	What	Sent	Status
JJ	Step B — beat touchups on the ~50-case validation cohort.	Step A sent 2026-05-19	to-send
Sadiyya Farooque	Answer DZHK Rückfragen to Verwendungsnachweis/Schlussbericht 81Z0200109 (Imaging 3.0).	delegated 2026-07-18	awaiting
Simon (Bohlender)	Data send/receive into RADICAL while scanning, latency-aware (WP3 I/O).	discussed 2026-06-28	running
Raphael	Build retraining + data/model versioning + Metrics-Reloaded pipeline; nnU-Net Track-1 SAX baseline.	2026-06-05	running
Thomas Koeck (Mainz) · +Göpfert	Review + return signed Auftrag-type contract (OLINK proteomics).	2026-06-01	awaiting
Raphael	UKB Cat 523 re-download.	2026-05-12	parked
Sadiyya Farooque	Forward Birkholz's reply on >50k€ procurement + ask Eike for case detail.	2026-06-02	parked

Note about delegations (autosaves; send when ready)

People coffee-machine cards 13

Hannah Tier A

On her plate (owner): —
Nudge: light.
(note: Hannah = HH; not QAH. QAH = Quang An Hong — the Claudia how-to is Quang's.)

works best with

routine, steady cadence; occasional reminder is enough. Low-maintenance.

Tilman (TR) Tier B

On his plate (owner): KW29 — Probandenbetrieb MRT (8 h, core) ✓; CPET-Auswertung/Nacharbeiten (in Arbeit, 2 h); SIGNET-Vorbereitung (SAP-APM Bestellung); Impression-Amendment-Vorbereitung; SAP-APM Status-Upgrade Prof. Nagel (Antrag); ORBIS-Nutzerantrag ✓, Institut-Bestellungen ✓, Schließrechte/Schlüssel ✓. ~16 h reported; template followed cleanly.
Waiting on you ←: — (nothing blocked).
Nudge: reminders help a lot — surface his items the morning before you see him.

works best with

clear asks + reminders — he's just-in-time and gets done what you tell him; a nudge lands well. Ask him for a short structured weekly status back (also feeds the month-of-Cowork efficiency push you gave him).

Denis Tier A

On his plate (owner): —
Nudge: light.

works best with

hands-off; delivers reasonably well. Visibility into actual load is low, but output is fine.

Simon Tier A

On his plate (owner): RADICAL-latency feasibility (imaging-4 WP3 I/O — weighing); integration with Raphael + Quang (nnU-Net / pipeline). (Claudia EOS-access task closed 2026-06-28.)
Nudge: low.

works best with

give him a problem, get out of the way. Self-assigns and stays well aligned.

Quang Tier A (over-delivers on what engages him)

On his plate (owner): KW29 self-report (submitted as Weekly_status_template.xlsx — no name/hours/most statuses filled): LV-wall repair algorithm (1st draft); auto-processing for dev orgs; batch-download; contour actions (marker-based delete, resize); Teaching-Cases upload (in Arbeit); LA-experiment prep for Alexandros (in Arbeit); VHR opening/closing-frame contour review; Neel pixel-values PR (target Mon). Perfusion self-paused ("higher-prio research/software") — the known coverage-risk item, deprioritised again.
Coverage risk (important-but-neglected — track these, not his flow): perfusion follow-through; closing loops with SOPs (e.g. LAX quantification); his MD-thesis — would open strong grant-writing.
Guides: Neel.

works best with

hand him the important problem; he'll often overrun the assignment on things he cares about (made the software ~5–10× faster). Lighter on what doesn't engage him.

Raphael Tier A-/support

On his plate (owner): KW29 — Training Pipeline (dataset-tracking, auto-dataset-selection→auto-training, Model-Storage open), self-listed blocked since KW27 (~2–3 wks), ~30 h; Model Training / draw contours (~2 h); owes Luisa the eval-pipeline review (Tue). Return barely filled — no name, no Status values, both items "Geblockt durch: Raphael" (self), totals/deadlines "tbd".
Guides: Luisa (under review — her KW29 next step is gated on his review; fresh evidence for the fit question).

works best with

bring the analytical scaffolding to discussions — picks things up and delivers, but is non-analytical in problem-solving; currently the weakest link in the engineering group. Open question: is he the right person to be guiding Luisa?

Luisa Tier J (HiWi, strong, early-career)

On her plate (owner): KW29 — GoetheCVI_MLflow evaluation pipeline: modular eval framework (metrics/runner/visualization) + MLflow logging + infra fixes (CPU-fallback, requirements); branch pushed, locally tested (18 h, in Arbeit); + additional-metrics extension (4 h) — pending RJ review (Tue). ~22 h; well-filled, hours present, ladders to thesis.
Waiting on you ←: — (next step gated on RJ, not EN).

works best with

she's very good and early in her career; thrives where she can grow. Currently guided by Raphael — guidance fit under review.

Neel Tier J (HiWi, strong)

On his plate (owner): KW29 — MDR software-test automation: Playwright test 20 (image identifications) ✓ 9 h; myocardial-pixel polar-coordinate system (in Arbeit, 12 h, from 17 Jul). ~21 h; two concrete verifiable items, hours filled — clean report (submitted as Weekly_status_template_Juli.xlsx).
Guided by: Quang (his pixel-coordinate work pairs with Quang's Neel pixel-values PR).

works best with

capable; takes on larger projects (e.g. automating the software tests required for MDR). Output is filtered through Quang, so completion visibility is partial.

Anna-Katharina (AK) — NEW, profile TBD (first return KW29)

Werkstudentin ("Anna" in SF reports); roster: not in the "Geblockt durch" dropdown (can't block anything). Actual work was flagged "unclear" — KW29 return reveals it: paper- and teaching-heavy, run largely by VP. Tier / working-style pending Eike.
On her plate (KW29): CPET-SOP finalize (w/ Til; 4 h/8 h, in Arbeit); CPET-Mittwochs Impression support ✓; Springer paper "Effort intolerance…" (1st draft → VP review); Springer paper "Preeclampsia as CV risk" (1st draft → VP review); Wahlfächer WS26/27 registration; two new elective-course pitches (M2 cardiology; Medical-English presentation training → VP weekly); ESC-Munich ePoster / voice-over / 3-min talk prep; ESC name correction.
Waiting on you ←: — (blocked on SF for ESC-Munich travel — train ticket, hotel-cost check, ticket-cost submission — since 2026-06-28, ~3 wks).
Flags: hours missing on almost all items; mis-used "Geblockt durch: mich" (self) on the two papers (not a valid blocker); scope reads above typical Werkstudentin level. One impossible date ("3036-08-03").
Nudge: TBD — confirm role/goal with VP + Eike.

Alex Tier J (onboarding, new 2026-07-09)

On his plate (owner): DECIPHER LA + LAX analysis — returned/done 2026-07-16 (briefed at kickoff, dataset access handed over).
Waiting on you ←: — (kickoff done).
Nudge: onboarding — set expectations at the first meeting.

works best with

TBD — scaffold created 2026-07-09, fill at first meeting.

Valentina Tier C (needs alignment)

On her plate (owner): (see 50-team/valentina/STATE.md).
Nudge: align, don't task-track.

works best with

discuss and agree content first — and emotionally — before she runs. A power-house who brings things into action fast; very quick to see that something doesn't work, slower to find the fix; dislikes ambiguity / grey values. Without agreed direction she can run full-speed the wrong way. Give her a clear ruleset to operate inside rather than open-ended todos.

Sadiyya Tier D → UNDER REVIEW (strong KW26 report 2026-06-29; watch whether it sustains)

Status: missed 5–6 Monday management meetings; asked for a weekly activity list → off sick ~2 weeks → back 2026-06-22, declined the management meeting citing inbox load. Prior read: likely past repair; replacement in motion (HiWi + TR).
KW26 update (2026-06-29): delivered the requested weekly activity list — 35 h, substantial: Finanz-/Personalkostenplanung 2026 complete, >100-mail inbox cleared + digital filing restructured, CMR End Letter, CMR-Retreat coordination, Deniz Reisekosten prep, FK-Z for VP's SE, VP Projektvertrag → ready for Leistner signature then Drittmittel. Caveat: much is "in Vorbereitung / zur Unterschrift bereit" (teed up, not closed) = the E9-coordination tier the HiWi+AI replacement targets. One strong week (and the first visible one) ≠ overturned pattern → watch 3–4 weeks before re-rating.
HiWi Mehrkosten / Umbuchung (Imaging 4.0): decided 2026-06-29 (unblocked — was her blocker). VP contract + Deniz Reisekosten just need downstream signatures.
Contract ends 12/2026 (confirmed 2026-06-23) — ~6 months runway. Structural call stands (role is HiWi+AI-replaceable); the strong week shifts the human handling toward using the runway well, not an early adversarial exit.
DECISION — how to proceed (use-up-until-12/2026 vs negotiated early exit; align HiWi + TR replacement to the 12/2026 cliff): 30-min session — now schedulable, now better-informed by KW26.
On her plate (owner): KW29 (prose docx, template NOT used → no status column / no hours / no waiting-since dates — the structure designed to fix the overstatement pattern is again absent): HiWi-Einstellungsanträge (Leistner-Freigabe); Arbeitsvertrag Raphael Reinstein (→ EN release → Leistner); HiWi-Unterlagen an HR + Nachreichungen; Hospitation Sofia Lakhlifa; Myoflame/CellTrend ELISA-USP + strategic-purchase justification + Angebotsanforderung; DZHK Imaging 3.0 VN (Nagel/Puntmann 2021–24 Reisekosten-Identifikation, Anforderungsvorlage, Freigabe-Mail an EN, Frachtkosten-Ablage); OLINK-Vertragsstatus (Köck); DZHK-Deadline-Meeting (Nachweisführung Pkt 4&5 übernommen). Content heavily teed-up ("Vorbereitung / zur Freigabe / Anforderung / Erstellung einer Vorlage") = advanced, not delivered.
Waiting on you ←: Raphael Reinstein contract "zur Freigabe bei Prof. Nagel" — framed as waiting-on-EN (same pattern as KW28; EN typically turns these around next day). NEW, untracked by SF: AK is blocked on SF for ESC-Munich travel (train ticket, hotel-cost check, ticket-cost submission) since 2026-06-28 (~3 wks). 2026-07-23: SF sent per-Punkt status of the DZHK Imaging 3.0 VN Rückfragen (2–5, Frachtkosten, Reisekosten), flagging where EN is needed → EN review + input before the 28.07 gate. 2026-07-28: EN wrote the fachliche Erläuterungen into the VN-Dokument (ticked done on the focus page); 28.07 gate met → delegation demoted to awaiting; confirm final DZHK submission (SF on leave).
Newly delegated (2026-07-18): answer DZHK Rückfragen to Verwendungsnachweis/Schlussbericht 81Z0200109 (Imaging) — hard deadline 28.07. EN part DONE 2026-07-28.
Nudge: Umbuchung decided 2026-06-29 → schedule the 30-min proceed-session.

Tier-D escalation ladder (the mechanism, applies to non-deliverers)

They produce their own list + timeframe + milestones (self-authored).
They self-check delivery against it.
Escalation fires on silence, not just self-declared misses — no status in N days, or a milestone date passed with nothing marked done → it surfaces in the morning overview on its own. (Designed so it runs without Eike initiating, and without the non-deliverer's cooperation.)

Note about people (autosaves; send when ready)

Strategy 3 active · 14 total

Proposed for next Fri 14:00: (set Friday topic in STRATEGY.md)

Work next — ranked

NEXTBad Orburgentself-imposed

German consolidation step — pulls Beyond + medneo + Am Turm into one place; local doctor runs the FFM back-office.
Generates revenue + de-risks the uni exit; bridges to the Mojácar longevity centre. Next: Eike's concrete move after the Strauss/Adel chats.
**Sequencing (Eike 2026-06-07):** do Bad Orb FIRST — asap with VP (next few days).
**(2026-06-11) Eike + VP executing directly this weekend (Sat/Sun)** — handled outside the Friday strategy block.

Cooperations (Eike's own research partnerships)high

**SCOPE (Eike 2026-07-03):** partnerships Eike wants for **his own research**. Inbound *via* the HFpEF focus group or ageing (e.g. **David Bode / DHZC**) is research-politics, NOT a cooperation — do not raise it here unless Eike flags it. (Bode moved to the focus-area track.)
**Eike's partner list (2026-07-03):** Berlin — Sebastian Kelle (CMR) · Berlin — Anja Hennemuth (AI) · EPC — Uwe Nixdorf (whole-body CMR, ~5000 + health eval + follow-up) · HZ Bad Bevensen — ??? (CMR) · Messina — Tommaso + Claudia (CMR: HR-cine, other) · Heidelberg — Florian Andre + Benjamin Meder (CMR: cardiomyopathies) · + more TBD.
**Prior-listed, confirm keep/drop:** Bender/Loewe IBT (AI) — was on the mid-June list, not on Eike's 03-Jul list. Scaffolding at 10-research/admin/research-politics/cooperations/.

⛔ blocked by: per partner — goal (data / grant co-app / IP / methods / co-authorship), what Eike gives, what he gets, status, push-timing.

Grantshighhard deadline

The funding ladder — €2.5M survival (2031–40) / €10–20M ambition. EN = AI-imaging, VP = trials.
Assembly started 2026-06-05 — keep momentum; longlist sequencing + DFG HFpEF Methods rewrite. Submission dates are hard.
**(2026-06-11)** New collaboration signal to fold in: **David Bode (DHZC)** — 120-pt transmyocardial + coronary-sinus + femoral paired sampling, invasive hemo + blood gas, HFpEF-rich, banked aliquots; collaboration-only (not a biobank). Strong wet-lab counterpart to leg-stress CMR energetics → hook to **DFG cmr-dyspnea-energetics** + **OLINK**. Otherwise next when time: **work the DFG grant**.

In the queue (not yet discussed)

CMR-AI product roadmap (Goethe CVI) — The spinoff product arc on top of the contour engine — what ships, in what order, MDR/FDA sequencing. Overlaps Contours + Imaging Project.
Branding — Eike + VP personal brand — uni prof + scientist + high-end practice + healthy-lifespan, AI-supported, evidence-based. Peter-Attia-style with chair-level research credentials. The brand is the people. Overlaps Bad Orb.
Task-list / brain-system cleanup — **(Eike 2026-06-18, via feedback)** "Clean up the whole task list." The flat TODO list has accreted project-status items that aren't actionable todos. Target shape: keep only the 3–5 todos a working session actually produces; everything else is either project status (lives in STATE.md, not the flat list) or a parked/triggered item. Likely touches `sweep_todos.py` bucketing + what the overview/task-console surface by default.
Reimbursement reconciliation ledger (Reisekosten + Barmenia) — **(Eike 2026-07-27, parked — "full to the rim today, bring up on a quieter day")** The recurring leak: no ledger tracking *spent → eingereicht → erstattet* per claim. Previous secretary → several 1000s € lost. Two gaps: paid-but-never-submitted (pure loss) and submitted-but-rejected. ⛔ decide scope (travel only vs + Barmenia) + where the "spent" column comes from (card/bank statements) — without it the tool only catches submitted-vs-reimbursed, not never-submitted (the bigger leak).

Show actioned — no intervention until trigger (7)

Full Imaging Projectuntil: Gantt needs a review

Milestones/timeframes/Gantt worked 2026-06-05; execution now flows via delegations + action points, not strategy.

Contours (CMR-AI segmentation)until: Luisa CorSeg verdict + Raphael nnU-Net baseline land

Company sell-blocker #1, but the strategy call (two-track: nnU-Net product + interactive correction; CineMA as pre-segmenter) is made. Execution is Raphael/Luisa. Includes "how to finalize the contours" (Goethe CVI).

MR-vendor strategyuntil: 2026-07-09 (parked 4 weeks — Eike 2026-06-11; resurface then)

Get a real alternative / second source away from the majors. Lens: field strength, cost, CMR depth, openness to external tools (own feedback loop + AI-supported scanning). Narrow eval to Canon Vantage Galan 3T + United Imaging 5T vs Siemens/GE baseline — see § MR vendor landscape below.
Includes SpinLab hyperpolarizer feasibility on the FFM Prisma (X-nucleus channel + dual-tuned coil + 13C sequences; SPINlab capital ~€1.5–2.5M; QP/pharmacist for human IMP release). Park as real eval if the Würzburg 22-Jun discussion points that way.
**(2026-06-07)** Keep the full vendor table; ALSO prepare a SHORT 3T + low-field version with a table of the key questions to start asking vendors. Back burner until the DFG grant is submitted, then activate vendor contact.
**(2026-06-11) Eike: low flame — after Grants. Park 4 weeks, do NOT show in the list, then bring back (resurface 2026-07-09).** (Resolves the unclear 06-09 note: this initiative = Eike's list-item #4.)

DZHK Professors — spokesperson roleuntil: after the Eike·Tanja·Ralf kick-off call (resurface to confirm slate + board pitch)

**Worked through 2026-06-09 (strategy session closed).** Eike elected speaker 2026-06-01 (term Jun 2026 – May 2028; Tanja Zeller outgoing, Ralf Gilsbach incoming). Strategy: two engines — (A) board-mandated tasks, Eike as router not labourer; (B) uninvited "DZHK view on X" position papers, mixed authorship.
Slate to the board: **AI** (Eike leads — flagship, "get invited"), sex & gender, sustainability, + staged healthy-longevity (round 2). Signature instrument = the connection map → offer the board a **portfolio map of the DZHK project database** (links / clusters / parallel-work / opportunities / holes); demo-first (public SE network) then ask for the DB.
Full record + pre-call brief → `10-research/admin/research-politics/dzhk-professors/STATE.md` + `outputs/2026-06-09_pre-call-brief_triumvirate.md`.

DZHK HFpEF focus-area (Focus group)until: 2026-07-15

Focus-area co-lead governance + cluster map. Scaffolding at 10-research/admin/research-politics/dzhk-hfpef-focus-area/.
**(2026-07-03) Eike: no strategy from us for the moment.** A retreat catch-up (Gabriele Schiattarella + Sandy Engelhardt + Eike) is set for **14 Jul** — do NOT bring up the retreat before then. **After the 14th, remind Eike to spend 30 min thinking about a HFpEF strategy** (resurface trigger = 2026-07-15).

trAIectoriesuntil: vehicle-structure decision (revisit when Bad Orb / Mojácar entity structure firms up)

New company? The persistent software layer (clinical-case-UI / trAIectory app) that runs on top of both Bad Orb and Mojácar — decide whether it's its own vehicle.
**(2026-06-11) Eike: decided — the Trajectories branding/naming was worked through 2026-06-09 / Tue; positioning locked (pending VP weekend sign-off). Folds into Branding execution; off the strategy queue for now.**

Longevity / Mojácar (long-term)until: Eike reactivates (he will bring it up actively)

The destination longevity centre (Spain) that Bad Orb funds the path to. Long-horizon; the eventual flagship.
**(2026-06-11) Eike: very low flame — park for now; he'll bring it up actively when ready.**

Add by dropping @strategy <topic> into any STATE.md, talkback, or tell Claude. Ranks, deadlines & states live in _morning/STRATEGY.md (Claude-maintained).

Note about Strategy (autosaves; send when ready)

Talk back to brain free-form

For things not in any list above. Type freely, pick a prefix, send. Autosaves between sessions.

Look at occasionally

→ Task console — every open task with a duration + importance ("I have 20 min, what fits?"), and the open-loops triage queue so notes/sidenotes don't sink.

Periodic reviews (open on the Mac): _morning/STRATEGY.md (Friday topics) · IDEAS.md (parked ideas) · dzhk-hfpef-focus-area/outputs/ (latest cluster map) · INDEX.md §8 (triage decisions pending) · 90-archive/ (anything to revive?)

Conventions: ?c? = discuss · @c = autonomous Claude action · @strategy = move to Strategy queue · ## TODO Claude = longer prompts. Ticked items hide + queue in browser → tap "Send to brain →" to fire one batch email.

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